In:
The Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 75, No. S1 ( 1984-05-01), p. S69-S69
Abstract:
Intracellular recording techniques were used to study the physiological responses of cochlear nucleus neurons in 32 pentobarbital anesthetized cats. Electrodes were filled with 2% to 4% horseradish peroxidase (HRP) in 0.5 M KCl. Each neuron was studied extracellularly by obtaining a tuning curve, determining the characteristic frequency (CF), and generating a peristimulus time histogram (PSTH) at the CF. After intracellular penetration, the PSTH at the CF was repeated to determine if any change in response had occurred. HRP was then iontophoretically injected intracellularly. Serial transverse frozen sections were incubated using a diaminobenzidine reaction intensified by preincubation with cobalt chloride. In the anteroventral cochlear nucleus (AVCN), three HRP-filled neurons were physiologically characterized. A bushy cell located in the AA region had a primarylike response at its CF of 4 kHz. An elongated stellate cell in the PD region of the AVCN had a primarylike response at its CF of 10 kHz at 90 dB, but at lower intensities (80–60 dB) the unit showed a progressive change to a chopperlike response. A small stellate cell along the medial border of PV in the AVCN showed an onset response at its CF of 4 kHz. In the dorsal cochlear nucleus (DCN), a horizontal giant cell showed a change from an onset pattern below its CF to an onset-sustained pattern at its CF of 10.5 kHz. The second HRP-marked cell in the DCN was a small broadly tuned (7–18 kHz) granule cell recorded in the molecular layer which showed a primarylike response at its CF of 14 kHz. [Support: NIH/NINCDS NS15860.]
Type of Medium:
Online Resource
ISSN:
0001-4966
,
1520-8524
Language:
English
Publisher:
Acoustical Society of America (ASA)
Publication Date:
1984
detail.hit.zdb_id:
1461063-2
