In:
Science Translational Medicine, American Association for the Advancement of Science (AAAS), Vol. 14, No. 657 ( 2022-08-10)
Abstract:
Patients with diabetes are at risk of kidney complications. Kobayashi et al. surveyed 25 circulating proteins in patient cohorts of both type 1 and type 2 diabetes and report that circulating neuroblastoma suppressor of tumorigenicity 1 (NBL1) protein is associated with 10-year risk for progression to end-stage kidney disease across multiple cohorts. This association was backed up by analysis of biopsied renal tissue. NBL1 may thus provide a noninvasive risk predictor for advanced diabetic kidney disease.
Type of Medium:
Online Resource
ISSN:
1946-6234
,
1946-6242
DOI:
10.1126/scitranslmed.abj2109
Language:
English
Publisher:
American Association for the Advancement of Science (AAAS)
Publication Date:
2022
