In:
Science Translational Medicine, American Association for the Advancement of Science (AAAS), Vol. 14, No. 657 ( 2022-08-10)
Abstract:
SARS-CoV-2 variants have evolved rapidly, particularly as populations develop immunity to prior variants through vaccination and infection. Hence, the ability of immunity elicited by one variant to confer protection against another requires investigation. Here, Halfmann et al. characterized the B.1.621 (Mu) variant of SARS-CoV-2, which was prevalent in the fall of 2021. The authors found that serum from vaccinated individuals neutralized the Mu variant, although at reduced potency compared to ancestral SARS-CoV-2. Hamsters that were previously infected with an early isolate were protected from infection with the Mu variant. These data support further evaluation of how prior immunity to one SARS-CoV-2 variant can protect against emerging variants.
Type of Medium:
Online Resource
ISSN:
1946-6234
,
1946-6242
DOI:
10.1126/scitranslmed.abm4908
Language:
English
Publisher:
American Association for the Advancement of Science (AAAS)
Publication Date:
2022