In:
Science Translational Medicine, American Association for the Advancement of Science (AAAS), Vol. 15, No. 693 ( 2023-04-26)
Abstract:
Current clinical methods for postoperative monitoring of soft tissue defect repair and digit replantation are often subjective or inaccurate, increasing the risk for surgical complications and failure. Here, Wu and colleagues designed an on-skin biosensor using a gradient crosslinked polymer. This system allowed for appropriate flexibility and sensitivity for adhesion to skin, accurate monitoring of blood flow, and sufficient rigidity for necessary electrical components. They demonstrated that these sensors could successfully detect vascular compromise in a variety of preclinical and clinical scenarios through pulse wave detection and analysis. These results suggest that on-skin biosensors may provide a simple, noninvasive, and unbiased method for the detection of vascular complications in postsurgical settings. —AW
Type of Medium:
Online Resource
ISSN:
1946-6234
,
1946-6242
DOI:
10.1126/scitranslmed.abq1634
Language:
English
Publisher:
American Association for the Advancement of Science (AAAS)
Publication Date:
2023