In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 52, No. 11 ( 2008-11), p. 4137-4140
Kurzfassung:
Metronidazole, which is used for the treatment of infections caused by anaerobic organisms, was evaluated in Mycobacterium tuberculosis -infected guinea pigs. M. tuberculosis can adapt to hypoxia, which is present in the primary lesions of infected guinea pigs. Metronidazole treatment (for 6 weeks at 100 mg/kg of body weight) resulted in no reduction in the bacillary burden and significantly worsened lesion inflammation.
Materialart:
Online-Ressource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.00196-08
Sprache:
Englisch
Verlag:
American Society for Microbiology
Publikationsdatum:
2008
ZDB Id:
1496156-8
SSG:
12
SSG:
15,3
