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Combination of Amphotericin B with Flucytosine Is Active In Vitro against Flucytosine-Resistant Isolates of Cryptococcus neoformans

Schwarz, Patrick ; Janbon, Guilhem ; Dromer, Françoise ; [weitere]

American Society for Microbiology ; 2007

In: Antimicrobial Agents and Chemotherapy Vol. 51, No. 1 ( 2007-01), p. 383-385

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In: Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 51, No. 1 ( 2007-01), p. 383-385

Kurzfassung: The combination of flucytosine and amphotericin B was tested against 10 flucytosine-resistant isolates of Cryptococcus neoformans by checkerboard, killing curves, and Etest. Although differences were observed depending on the technique used, antagonism was never observed. The synergistic interaction was related to the mechanism of flucytosine resistance of the isolates.

Materialart: Online-Ressource

ISSN: 0066-4804 , 1098-6596

URL: Article

DOI: 10.1128/AAC.00446-06

RVK:

XA 24552

Sprache: Englisch

Verlag: American Society for Microbiology

Publikationsdatum: 2007

ZDB Id: 1496156-8

SSG: 12

SSG: 15,3