In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 56, No. 12 ( 2012-12), p. 6393-6396
Abstract:
We investigated the frequency and clinical significance of macrolide resistance in adult and pediatric patients with community-acquired pneumonia from a Mycoplasma pneumoniae infection. The frequency of the A2063G mutation in the 23S rRNA gene was significantly higher in children than in adults (61.3% [19/31] and 13.3% [8/60], respectively; P 〈 0.001). Patients with macrolide-resistant M. pneumoniae infections showed a longer duration of fever ( P = 0.021) and required a longer duration of antibiotic treatment ( P = 0.007).
Type of Medium:
Online Resource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.01421-12
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
2012
detail.hit.zdb_id:
1496156-8
SSG:
12
SSG:
15,3