In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 48, No. 10 ( 2004-10), p. 3736-3742
Kurzfassung:
Three types of multidrug-resistant Escherichia coli isolates, called GEN S, GEN R, and AMG S, according to their three different aminoglycoside resistance patterns, were responsible for urinary tract colonization or infection in 87, 12, and 13 new patients, respectively, in a French 650-bed geriatric hospital over a 13-month period. The three E. coli types belonged to the same clone and phylogenetic group (group B2) and had identical transferable plasmid contents (a 120-kb plasmid), β-lactam and fluoroquinolone resistance genotypes ( bla TEM-1B , bla CTX-M-15 , and double mutations in both the gyrA and the parC genes), and virulence factor genotypes ( aer , fyuA , and irp2 ). They disseminated in the geriatric hospital, where the antibiotics prescribed most often were fluoroquinolones and ceftriaxone, but not in the affiliated acute-care hospital, where isolation precautions were applied to the transferred patients. Thus, E. coli isolates, both CTX-M-type β-lactamase producers and fluoroquinolone-resistant isolates, might present a new challenge for French health care settings.
Materialart:
Online-Ressource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.48.10.3736-3742.2004
Sprache:
Englisch
Verlag:
American Society for Microbiology
Publikationsdatum:
2004
ZDB Id:
1496156-8
SSG:
12
SSG:
15,3
