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Bactericidal Activities of R207910 and Other Newer Antimicrobial Agents against Mycobacterium leprae in Mice

Ji, Baohong ; Chauffour, Aurélie ; Andries, Koen ; [weitere]

American Society for Microbiology ; 2006

In: Antimicrobial Agents and Chemotherapy Vol. 50, No. 4 ( 2006-04), p. 1558-1560

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In: Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 50, No. 4 ( 2006-04), p. 1558-1560

Kurzfassung: As measured by a proportional bactericidal technique in the mouse footpad system, the bactericidal activity against Mycobacterium leprae of R207910 was equal to that of rifapentine, rifampin, or moxifloxacin and significantly greater than those of minocycline, PA-824, and linezolid. These data suggest that R207910 may play an important role in treatment of leprosy.

Materialart: Online-Ressource

ISSN: 0066-4804 , 1098-6596

URL: Article

DOI: 10.1128/AAC.50.4.1558-1560.2006

RVK:

XA 24552

Sprache: Englisch

Verlag: American Society for Microbiology

Publikationsdatum: 2006

ZDB Id: 1496156-8

SSG: 12

SSG: 15,3