In:
Journal of Clinical Microbiology, American Society for Microbiology, Vol. 37, No. 3 ( 1999-03), p. 788-791
Abstract:
To study possible nosocomial transmission of multidrug-resistant (MDR) Mycobacterium tuberculosis , strain types and other information on 24, mostly human immunodeficiency virus-positive patients, were collected. Isolates from 11 patients had identical IS 6110 restriction fragment length polymorphism (RFLP) patterns as well as spoligotype patterns and resistance profiles. Noticeably, nine other isolates from related cases also exhibited identical spoligotypes but slightly different RFLP patterns. These results indicate that for some MDR strains, the evolutionary clock of IS 6110 RFLP may run too fast for reliable interpretation of strain typing results over a period of a few years.
Type of Medium:
Online Resource
ISSN:
0095-1137
,
1098-660X
DOI:
10.1128/JCM.37.3.788-791.1999
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
1999
detail.hit.zdb_id:
1498353-9
SSG:
12