In:
Journal of Virology, American Society for Microbiology, Vol. 75, No. 2 ( 2001-01-15), p. 1065-1071
Abstract:
Using HLA-peptide tetrameric complexes, we isolated human T-cell lymphotrophic virus type 1 Tax peptide-specific CD8 + T cells ex vivo. Antigen-specific amino acid motifs were identified in the T-cell receptor Vβ CDR3 region of clonally expanded CD8 + T cells. This result directly confirms the importance of the CDR3 region in determining the antigen specificity in vivo.
Type of Medium:
Online Resource
ISSN:
0022-538X
,
1098-5514
DOI:
10.1128/JVI.75.2.1065-1071.2001
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
2001
detail.hit.zdb_id:
1495529-5