In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 67, No. 6 ( 2023-06-15)
Kurzfassung:
The number of dermatophytosis cases resistant to terbinafine is increasing all over the world. Therefore, there is a need for antifungal susceptibility testing of dermatophytes for better management of the patients. In the present study, we have evaluated a gradient test (GT) method for testing the susceptibility of dermatophytes to terbinafine. MIC values to terbinafine determined by the EUCAST reference technique and by gradient test were compared for 79 Trichophyton spp. isolates. Overall, MICs were lower with gradient test (MIC 50 of 0.002 μg/mL) than with EUCAST (MIC 50 of 0.016 μg/mL). Good categorical agreement ( 〉 90%) between the 2 techniques was obtained but the essential agreement was variable depending on the batch of gradient test.
Materialart:
Online-Ressource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/aac.01716-22
Sprache:
Englisch
Verlag:
American Society for Microbiology
Publikationsdatum:
2023
ZDB Id:
1496156-8
SSG:
12
SSG:
15,3
