In:
Collection of Czechoslovak Chemical Communications, Institute of Organic Chemistry & Biochemistry, Vol. 56, No. 11 ( 1991), p. 2352-2361
Kurzfassung:
The reactions of tert-butyl-3-acetoxymethyl-3-cephem-7-diazocephalosporanate 1,1-dioxide ( I ) with acetaldehyde, benzaldehyde, 2-thiophene caboxaldehyde, 3-thiophene carboxaldehyde, 2-furan carboxaldehyde, 3-furan carboxaldehyde and isobutyraldehyde have been studied. Use of boron trifluoride etherate as a catalyst for these reactions was found to accelerate the reactions markedly and to favour the formation of aldehydes rather than the ketones at C-7 position as the carbonyl product. The products obtained from these reactions and the ratios of carbonyl products to epoxides suggest that the R groups of the carbonyl component have profound influence on the reactions.
Materialart:
Online-Ressource
ISSN:
0010-0765
,
1212-6950
DOI:
10.1135/cccc19912352
Sprache:
Englisch
Verlag:
Institute of Organic Chemistry & Biochemistry
Publikationsdatum:
1991
