In:
BMJ, BMJ
Abstract:
To estimate the incidence, risk factors, and
outcomes associated with in-hospital cardiac arrest and cardiopulmonary resuscitation in
critically ill adults with coronavirus disease 2019 (covid-19). Design Multicenter cohort study. Setting Intensive care units at 68 geographically
diverse hospitals across the United States. Participants Critically ill adults (age ≥18 years) with
laboratory confirmed covid-19. Main outcome measures In-hospital cardiac arrest within 14 days of
admission to an intensive care unit and in-hospital mortality. Results Among 5019 critically ill patients with
covid-19, 14.0% (701/5019) had in-hospital cardiac arrest, 57.1% (400/701) of whom received
cardiopulmonary resuscitation. Patients who had in-hospital cardiac arrest were older (mean age 63
(standard deviation 14) v 60 (15)
years), had more comorbidities, and were more likely to be admitted to a hospital with a smaller
number of intensive care unit beds compared with those who did not have in-hospital cardiac arrest.
Patients who received cardiopulmonary resuscitation were younger than those who did not
(mean age 61 (standard deviation 14) v 67 (14) years). The most common
rhythms at the time of cardiopulmonary resuscitation were pulseless electrical activity
(49.8%, 199/400) and asystole (23.8%, 95/400). 48 of the 400 patients (12.0%) who received cardiopulmonary resuscitation survived to hospital
discharge, and only 7.0% (28/400) survived to hospital discharge with normal or mildly impaired
neurological status. Survival to hospital discharge differed by age, with 21.2% (11/52) of
patients younger than 45 years surviving compared with 2.9% (1/34) of those aged 80 or older. Conclusions Cardiac arrest is common in critically ill
patients with covid-19 and is associated with poor survival, particularly among older patients.
Type of Medium:
Online Resource
ISSN:
1756-1833
Language:
English
Publisher:
BMJ
Publication Date:
2020
detail.hit.zdb_id:
1479799-9
