In:
Gut, BMJ, Vol. 71, No. 2 ( 2022-02), p. 238-253
Abstract:
Helicobacter pylori infection is mostly a
family-based infectious disease. To facilitate its prevention and management, a national consensus meeting was held to review current
evidence and propose strategies for population-wide and family-based H. pylori infection control
and management to reduce the related disease burden. Methods Fifty-seven experts from 41 major universities and institutions in
20 provinces/regions of mainland China were invited to review evidence and modify statements using Delphi process and grading of
recommendations assessment, development and evaluation system. The consensus level was defined as ≥80% for agreement on the proposed
statements. Results Experts discussed and modified the original 23 statements on
family-based H. pylori infection
transmission, control and management, and reached consensus on 16 statements. The final report consists of three parts: (1) H.
pylori infection and transmission among family members,
(2) prevention and management of H.
pylori infection in children and elderly people within
households, and (3) strategies for prevention and management of H. pylori infection for family members.
In addition to the ‘test-and-tre at’ and ‘screen-and-treat’ strategies,
this consensus also introduced a novel third ‘family-based H. pylori infection control
and management’ strategy to prevent its intrafamilial transmission and development of related diseases. Conclusion H. pylori is transmissible from person to
person, and among family members. A family-based H.
pylori prevention and eradication strategy would be a
suitable approach to prevent its intra-familial transmission and related diseases. The notion and practice would be beneficial not only for
Chinese residents but also valuable as a reference for other highly infected areas.
Type of Medium:
Online Resource
ISSN:
0017-5749
,
1468-3288
DOI:
10.1136/gutjnl-2021-325630
Language:
English
Publisher:
BMJ
Publication Date:
2022
detail.hit.zdb_id:
1492637-4
