In:
American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 198, No. 3 ( 1960-03-01), p. 471-475
Abstract:
When cold acclimating rats are treated with diathermy, curare and a combination of both, two main fractions of the increase in cold-induced oxygen consumption can be delineated. First, a fraction which diathermy replaces by virtue of the fact that it, in the intensities used, can raise core temperature without altering the temperature of the skin; therefore this fraction appears to be dependent upon changes in central temperature and is found to persist throughout the period of acclimation investigated. Second, a fraction of cold-induced oxygen consumption which is not replaced by diathermy and which is presumed to be dependent upon changes in skin temperature. By the administration of curare, this second fraction can be separated into two further fractions acting reciprocally depending upon the duration of cold exposure. In the early stages of acclimation, the curare-suppressed fraction of oxygen consumption appears to be entirely due to shivering. As shivering disappears with acclimation, it is replaced by a peripherally regulated nonshivering heat source which eventually takes over all the duties of heat production previously performed by shivering.
Type of Medium:
Online Resource
ISSN:
0002-9513
DOI:
10.1152/ajplegacy.1960.198.3.471
Language:
English
Publisher:
American Physiological Society
Publication Date:
1960
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12
