In:
American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 202, No. 6 ( 1962-06-01), p. 1090-1094
Abstract:
Blood pressure responses to alteration in blood flow were studied in the completely isolated, excised liver of the calf during perfusion of the hepatic artery or portal vein. The pressure-flow curves in both of the afferent vessels of the liver are curvilinear, with concavity toward the pressure axis. Resistance increases progressively with increases in perfusion rate; resistance increases are proportionately of greater magnitude than the increases in blood flow demonstrating autoregulation in both hepatic arterial and portal venous systems. The autoregulatory nature of pressure-flow responses is not affected by prolonged perfusion or marked acidosis.
Type of Medium:
Online Resource
ISSN:
0002-9513
DOI:
10.1152/ajplegacy.1962.202.6.1090
Language:
English
Publisher:
American Physiological Society
Publication Date:
1962
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SSG:
12
