In:
International Journal of Nephrology, Hindawi Limited, Vol. 2012 ( 2012), p. 1-7
Abstract:
Background . To address the cause(s) of the significant differences in chloride (Cl - ) concentrations between point-of-care blood gas analyzers and central laboratory analyzers. Methods . Cl - concentrations measured simultaneously by a blood gas analyzer (ABL800 FLEX) and a central laboratory analyzer (Hitachi7600) were collected in patients with severe acidemia ( pH 〈 7.20 ) ( n = 32 ) and were examined for correlations between differences in Cl - and factors associated with the acid-base status. Cl - concentrations were measured with both analyzers for samples with different concentrations of lactate, inorganic phosphate, or bicarbonate ( HCO 3 − ). Results . The differences in Cl - concentrations were correlated with HCO 3 − concentrations ( r = 0.72 , P 〈 0.0001 ) and anion gap ( r = 0.69 , P 〈 0.0001 ). Only the addition of HCO 3 − proportionately increased Cl - levels measured by a Hitachi7600, but it did not affect those measured by an ABL800FLEX. Conclusion . Cl - measurements with some analyzers may be influenced by HCO 3 − concentrations, which could result in the observed discrepancies.
Type of Medium:
Online Resource
ISSN:
2090-214X
,
2090-2158
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2012
detail.hit.zdb_id:
2573904-9