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    In: Parkinson's Disease, Hindawi Limited, Vol. 2018 ( 2018-07-22), p. 1-7
    Kurzfassung: Objective . Deep brain stimulation (DBS) surgery has increasingly been performed for the treatment of movement disorders and is associated with a wide array of complications. We aimed to present our experience and discuss strategies to minimize adverse events in light of this contemporary series and others in the literature. Methods . A retrospective chart review was conducted to collect data on age, sex, indication, operation date, surgical technique, and perioperative and late complications. Results . A total of 181 patients (113 males, 68 females) underwent DBS implantation surgery (359 leads) in the past six years. Indications and targets were as follows: Parkinson’s disease (STN) ( n = 159 ), dystonia (GPi) ( n = 13 ), and essential tremor (Vim) ( n = 9 ). Mean age was 55.2 ± 11.7 (range 9–74) years. Mean follow-up duration was 3.4 ± 1.6 years. No mortality or permanent morbidity was observed. Major perioperative complications were confusion (6.6%), intracerebral hemorrhage (2.2%), stroke (1.1%), and seizures (1.1%). Long-term adverse events included wound (7.2%), mostly infection, and hardware-related (5.5%) complications. Among several factors, only surgical experience was found to be related with overall complication rates (early period: 31% versus late period: 10%; p = 0.001 ). Conclusion . The rates of both early and late complications of DBS surgery are acceptably low and decrease significantly with cumulative experience.
    Materialart: Online-Ressource
    ISSN: 2090-8083 , 2042-0080
    Sprache: Englisch
    Verlag: Hindawi Limited
    Publikationsdatum: 2018
    ZDB Id: 2573854-9
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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