In:
Cancer Research, American Association for Cancer Research (AACR), Vol. 74, No. 19_Supplement ( 2014-10-01), p. 281-281
Kurzfassung:
Objectives: There have been few studies on medical radiation work history factors and cancer mortality. In this nationwide prospective cohort study of United States radiologic technologists, we expanded our previous evaluation of work history and cancer mortality risks, by extending follow-up by 11 years and examining a broader range of cancers. Methods: Using Cox proportional hazards models, we estimated cancer mortality risks through 2008 according to work history and other data derived from questionnaire responses provided during 1983-89 by 90,268 U.S. radiologic technologists. We controlled for potential confounding by age, birth year, pack-years of cigarettes smoked, body mass index, race, and gender. Results: There were 9,564 deaths and 3,329 deaths from cancer. After controlling for potential confounding factors, we found that technologists who began working before 1950 had marginally increased risk of dying from all cancers (p-trend=0.08), as well as increased risk of dying from female breast cancer (p-trend=0.01) and stomach cancer (p-trend=0.01) compared to those who began working in 1970 or later. Other work history factors, including starting work at a younger age, working greater number of years, or holding patients for x-rays more often, were not consistently associated with increased cancer mortality risks. Conclusions: We found that radiologic technologists who worked before 1950 had increased risk of dying from certain cancers, which may reflect higher occupational radiation exposures before the late 1950s. Note: This abstract was not presented at the meeting. Citation Format: Jason J. Liu, Michele M. Doody, Mark P. Little, D Michal Freedman, Bruce H. Alexander, Cari M. Kitahara, Alice J. Sigurdson, Terrence Lee, Preetha Rajaraman, Jeremy S. Miller, Diane M. Kampa, Steven L. Simon, Dale L. Preston, Martha S. Linet. Work history and cancer mortality risks in 90,268 United States radiologic technologists. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 281. doi:10.1158/1538-7445.AM2014-281
Materialart:
Online-Ressource
ISSN:
0008-5472
,
1538-7445
DOI:
10.1158/1538-7445.AM2014-281
Sprache:
Englisch
Verlag:
American Association for Cancer Research (AACR)
Publikationsdatum:
2014
ZDB Id:
2036785-5
ZDB Id:
1432-1
ZDB Id:
410466-3
