In:
Neuroepidemiology, S. Karger AG, Vol. 21, No. 1 ( 2002), p. 36-43
Abstract:
We have conducted annual health checkup surveys of elderly subjects aged 60 years or older in a remote island of southwestern Japan. After excluding patients with neurological diseases and the subjects who needed help in activities of daily living, a cross-sectional analysis of the data obtained from 348 elderly people aged 60–89 years was made. We examined the age and sex distributions of abnormal neurological findings, including the scores of the Mini-Mental State Examination (MMSE). In this study, aging was associated with muscle weakness in the lower limbs, cerebellar dysfunction, hand tremor, decrease in handgrip, abnormality of deep sensation and a decrease in the MMSE score. These findings suggest a characteristic pattern of nervous system deterioration with age. We discuss the possible pathogenesis and significance of these findings that should contribute to a better understanding of normal aging in the nervous system.
Type of Medium:
Online Resource
ISSN:
0251-5350
,
1423-0208
Language:
English
Publisher:
S. Karger AG
Publication Date:
2002
detail.hit.zdb_id:
1483032-2