In:
Cells Tissues Organs, S. Karger AG, Vol. 136, No. 4 ( 1989), p. 279-284
Abstract:
The neuropeptide Y (NPY) immunoreactive synaptic input to neurons containing neurophysin II (NPII) the carrier protein of vasopressin (VP) was observed in the paraventricular nucleus (PVN) of the rat hypothalamus by double-labeling immunocytochemistry combining the preembedding peroxidase-antiperoxidase (PAP) method with the postembedding immunogold staining method at the electron-microscopic level. NPY-like immunoreactivities were detected by the PAP method in the dense granular vesicles (70–100 nm in diameter) in the immunoreactive presynaptic axon terminals. NPY-like immunoreactive large neurosecretory granules labeled with gold particles were found in the neurons receiving synaptic input of the NPY-like immunoreactive terminals. This suggests that NPY may be a neuro-transmitter or neuro modulator and that NPY neurons may through synaptic contacts regulate the secretion of VP neurons.
Type of Medium:
Online Resource
ISSN:
1422-6405
,
1422-6421
Language:
English
Publisher:
S. Karger AG
Publication Date:
1989
detail.hit.zdb_id:
1481840-1
SSG:
12
