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    In: International Archives of Allergy and Immunology, S. Karger AG, Vol. 158, No. 2 ( 2012), p. 175-183
    Abstract: 〈 i 〉 Background: 〈 /i 〉 The prevalence rates of smoking in subjects with asthma have frequently been reported as similar to those in the general population; however, available data are not up-to-date. There is only limited and somewhat conflicting information on the long-term effects of smoking on health outcomes among population-based cohorts of subjects with asthma. We aimed to investigate changes in smoking habits and their effects on forced expiratory volume in 1 s (FEV 〈 sub 〉 1 〈 /sub 〉 ) in subjects with asthma in comparison with the rest of the population, focusing on the healthy smoker effect. 〈 i 〉 Methods: 〈 /i 〉 We studied 9,092 subjects without asthma and 1,045 with asthma at baseline who participated in both the European Community Respiratory Health Survey I (20–44 years old in 1991–1993) and II (1999–2002). 〈 i 〉 Results: 〈 /i 〉 At follow-up, smoking was significantly less frequent among subjects with asthma than in the rest of the population (26 vs. 31%; p 〈 0.001). Subjects with asthma who were already ex-smokers at the beginning of the follow-up in the 1990s had the highest mean asthma score (number of reported asthma-like symptoms, range 0–5), probably as a result of the healthy smoker effect (2.80 vs. 2.44 in never smokers, 2.19 in quitters and 2.24 in smokers; p 〈 0.001). The influence of smoking on FEV 〈 sub 〉 1 〈 /sub 〉 decline did not depend on asthma status. Smokers had the highest proportion of subjects with chronic cough/phlegm (p 〈 0.01). 〈 i 〉 Conclusion: 〈 /i 〉 One out of 4 subjects with asthma continues smoking and reports significantly more chronic cough and phlegm than never smokers and ex-smokers. This stresses the importance of smoking cessation in all patients with asthma, even in those with less severe asthma.
    Type of Medium: Online Resource
    ISSN: 1018-2438 , 1423-0097
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2012
    detail.hit.zdb_id: 1482722-0
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