In:
Dementia and Geriatric Cognitive Disorders, S. Karger AG, Vol. 33, No. 1 ( 2012), p. 11-17
Abstract:
〈 i 〉 Objective: 〈 /i 〉 The aim of this study was to identify the factors associated with differences between how Alzheimer’s disease (AD) patients and their caregivers rate the patient’s health-related quality of life (QoL). 〈 i 〉 Methods: 〈 /i 〉 Cross-sectional, multicentre study. Patients were 65 years or more, suffering from mild to moderate AD, native French speakers, with a main caregiver. Interrater agreement of the QoL-AD was assessed using the intraclass coefficient. A generalised linear model was used to identify factors related to the difference in health-related QoL scores between patients and their caregivers. 〈 i 〉 Results: 〈 /i 〉 The 122 patients of the study were 82 ± 6 years old and mainly women (69%). Independent factors related to the difference between patients and caregivers were: Mini Mental State Exam score (β = 0.32; 95% CI = 0.05–0.59); instrumental activities of daily living score (β = –0.61; 95% CI = –1.14 to –0.07); total Neuropsychiatric Inventory score (β = 0.10; 95% CI = 0.05–0.59), and Zarit’s burden score (β = 0.09; 95% CI = 0.01–0.17). 〈 i 〉 Conclusion: 〈 /i 〉 Practitioners must take into account the trend towards underestimation when health-related QoL is rated by caregivers or proxies.
Type of Medium:
Online Resource
ISSN:
1420-8008
,
1421-9824
Language:
English
Publisher:
S. Karger AG
Publication Date:
2012
detail.hit.zdb_id:
1482186-2