In:
Digestive Surgery, S. Karger AG, Vol. 29, No. 2 ( 2012), p. 92-98
Abstract:
〈 i 〉 Background: 〈 /i 〉 To examine recent trends in gallbladder cancer (GBC) in the general population in the Western world, cancer registration data on GBC in the Netherlands were analyzed. 〈 i 〉 Methods: 〈 /i 〉 Trends in incidence, treatment and survival, according to gender, age and stage of disease, between 1989 and 2008 for 3,917 patients were studied. Rates were age-standardized to the European standard population (European Standardized Rates – ESR). 〈 i 〉 Results: 〈 /i 〉 The incidence rate for GBC in the Netherlands decreased rapidly during the period of 1989–2008, except for males younger than 60 years. Overall survival remained stable, short-term (3-month) and long-term (5-year) relative survival among surgically treated patients increased significantly. Treatment patterns for GBC changed. Surgery decreased from 55% in 1989 to 38% in 2008 (p 〈 0.001). Chemotherapy and/or irradiation increased from 1.0 to 5.8% (p 〈 0.001). Receiving best supportive care increased from 44% in 1989 to 57% in 2008 (p 〈 0.001). 〈 i 〉 Conclusion: 〈 /i 〉 The incidence rate for GBC in the Netherlands has decreased rapidly. Treatment patterns for GBC have changed and survival among surgically treated patients has increased.
Type of Medium:
Online Resource
ISSN:
0253-4886
,
1421-9883
Language:
English
Publisher:
S. Karger AG
Publication Date:
2012
detail.hit.zdb_id:
1468560-7