In:
Cardiology, S. Karger AG, Vol. 140, No. 4 ( 2018), p. 227-236
Kurzfassung:
〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Micro-vascular occlusion (MVO) in a myocardial infarction (MI) is associated with an increased risk of heart failure and mortality. Hs-T-troponin has a double peak kinetic after MI. The aim was to determine if this kinetic was correlated to MVO evaluated by cardiac magnetic resonance imaging (MRI) after MI. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 This is a monocentric retrospective study. Inclusion criteria were hospitalization for MI, Thrombolysis In Myocardial Infarction flow 0 at coronary angiography, reperfusion within 12 h from the onset of chest pain, cardiac MRI within the first month, and a 5-days’ biological follow-up with at least hs-T-Troponin and C-reactive protein (CRP). Statistics were performed using the R software. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Ninety-eight patients were included. Fifty-three patients (54.1%) had MVO at MRI. The existence of MVO was associated with a trend of more kissing procedure during primary percutaneous coronary intervention ( 〈 i 〉 p 〈 /i 〉 = 0.06), a significantly more frequent second peak of troponin ( 〈 i 〉 p 〈 /i 〉 = 0.048), a significantly higher CRP level ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.0001) and a longer time to balloon ( 〈 i 〉 p 〈 /i 〉 = 0.01). The association of CRP level above 40 mg/L at day 2 and the observation of a second peak of troponin were associated to 95% of MVO in ST-segment elevation MI patients. By contrast, in the absence of these 2 criteria, MVO was absent in 78% of the cases. This score was associated with a higher rate of hospitalisation at 2 years. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 A biological score integrating hs-TNT second peak and CRP might help to predict MVO and predict outcomes after reperfused MI in our population.
Materialart:
Online-Ressource
ISSN:
0008-6312
,
1421-9751
Sprache:
Englisch
Verlag:
S. Karger AG
Publikationsdatum:
2018
ZDB Id:
1482041-9
