In:
Case Reports in Oncology, S. Karger AG, Vol. 14, No. 2 ( 2021-6-17), p. 906-911
Abstract:
Liver abscess formation is one of the major complications following radiofrequency ablation (RFA) in patients with hepatocellular carcinoma (HCC). 〈 i 〉 Clostridium perfringens 〈 /i 〉 is a rare but fatal (mortality rate: 70–100%) organism that could lead to severe sepsis. We presented a case where a 63-year-old woman with diabetes mellitus, hypertension, chronic hepatitis B-related cirrhosis in Child-Pugh class A and HCC with initial TNM stage II who had undergone 2 sessions of transarterial chemoembolization. RFA was performed for 4 small HCC due to poor effect of previous transarterial chemoembolization. However, all 4 treated tumors developed liver abscesses presenting with septic shock within 1 day. Aspirated abscesses and blood culture both yielded 〈 i 〉 C. perfringens 〈 /i 〉 infection. After intensive care, optimal intravenous antibiotic, and abscesses aspiration, the patient recovered successfully. All tumors achieved complete response during the follow-up period without local recurrence. The clinical presentations and risk factors of 〈 i 〉 C. perfringens 〈 /i 〉 -related liver abscess after RFA will be discussed in this manuscript.
Type of Medium:
Online Resource
ISSN:
1662-6575
Language:
English
Publisher:
S. Karger AG
Publication Date:
2021
detail.hit.zdb_id:
2458961-5
