In:
Arteriosclerosis, Thrombosis, and Vascular Biology, Ovid Technologies (Wolters Kluwer Health), Vol. 24, No. 6 ( 2004-06), p. 1068-1073
Abstract:
We investigated the contribution of interleukin-1 receptor antagonist (IL-1Ra) to atherosclerosis by comparing apolipoprotein E single knockout (IL-1Ra+/+/apoE−/−) with IL-1Ra+/−/apoE−/− mice. Immunostaining at age 32 weeks old showed an 86% increase in the MOMA-2–stained lesion area of IL-1Ra+/−/apoE−/−, whereas α-actin staining was significantly diminished compared with IL-1Ra+/+/apoE−/− mice.
Type of Medium:
Online Resource
ISSN:
1079-5642
,
1524-4636
DOI:
10.1161/01.ATV.0000127025.48140.a3
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2004
detail.hit.zdb_id:
1494427-3