In:
Arteriosclerosis, Thrombosis, and Vascular Biology, Ovid Technologies (Wolters Kluwer Health), Vol. 25, No. 8 ( 2005-08), p. 1590-1595
Abstract:
We found that in isolated skeletal muscle arterioles of PECAM-1 knockout mice the NO-mediated dilations to high temporal gradients of wall shear stress is reduced. Thus, we propose a role for PECAM-1 in the ability of the endothelium to sense high temporal gradients of shear stress which is coupled with NO-mediated vasodilation.
Type of Medium:
Online Resource
ISSN:
1079-5642
,
1524-4636
DOI:
10.1161/01.ATV.0000170136.71970.5f
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2005
detail.hit.zdb_id:
1494427-3