In:
Arteriosclerosis, Thrombosis, and Vascular Biology, Ovid Technologies (Wolters Kluwer Health), Vol. 29, No. 12 ( 2009-12), p. 2021-2027
Abstract:
The role of TWEAK and its receptor Fn14 were investigated in a mouse model of atherosclerosis. Treatment with an Fn14-Fc fusion protein to inhibit TWEAK resulted in advanced plaques with an increased abundance of macrophages and smaller macrophage size. Blocking TWEAK inhibited macrophage uptake of modified lipids in vitro.
Type of Medium:
Online Resource
ISSN:
1079-5642
,
1524-4636
DOI:
10.1161/ATVBAHA.109.195040
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2009
detail.hit.zdb_id:
1494427-3