In:
Stroke, Ovid Technologies (Wolters Kluwer Health), Vol. 50, No. Suppl_1 ( 2019-02)
Abstract:
Background and Purpose: Clinical outcomes after successful endovascular therapy in patients with acute ischemic stroke are associated with several factors including onset-to-reperfusion time (ORT). The objective of the current study was to assess whether ORT is associated with outcomes in elderly. Methods: Among 2420 patients enrolled in the RESCUE 2 study, a prospective stroke registry with acute cerebral large-vessel occlusion at 46 centers between October 2014 and January 2017, we enrolled 397 elderly patients more than 80 with successful reperfusion after thrombectomy (thrombolysis in cerebral infarction [TICI] score of 2b or 3) in the current analysis. The rates of good outcome (modified Rankin Scale [mRS] scores of 0-2 at 3 months) were compared among the three categories of ORT ( 〈 180 minutes, 180-239 minutes, and ≥240 minutes). We developed multivariate logistic regression model to assess the independent association of the ORT with good outcome by adjusting for clinically relevant factors. Results: The rates of good outcome were 41% (30/73), 34% (26/77), and 25% (62/247) in each category of ORT. Odds ratio and 95% confidence interval for good outcome were 0.68 and 0.49-0.94 per 1 category delay. Conclusion: ORT was associated with good outcome even in elderly patients.
Type of Medium:
Online Resource
ISSN:
0039-2499
,
1524-4628
DOI:
10.1161/str.50.suppl_1.WP46
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2019
detail.hit.zdb_id:
1467823-8