In:
Journal of Biomedical Nanotechnology, American Scientific Publishers, Vol. 18, No. 3 ( 2022-03-01), p. 807-817
Kurzfassung:
How to develop near-infrared second window (NIR-II, 1000–1700 nm) fluorescent nanoprobes with a uniform size, strong fluorescence signal and good biosafety owns great clinical requirement. Herein we reported that a two photon fluorescent nanoprobe was developed via encapsulating
NIR-II-fluorescent molecules into DSPE-PEG, which was effectively endocytosized by cancer cells, and achieved strong NIR-II fluorescence imaging in cancer cells and cancer cell-beard mice models. Prepared NIR-II-fluorescent nanoprobe exhibited rapid metabolism and excellent biocompatibility. In conclusion, the prepared two photon nanoprobe owns good biosafety, and clinical translational prospect in NIR-II fluorescent imaging of tumour in vivo in near future.
Materialart:
Online-Ressource
ISSN:
1550-7033
DOI:
10.1166/jbn.2022.3275
Sprache:
Englisch
Verlag:
American Scientific Publishers
Publikationsdatum:
2022
