In:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, SAGE Publications, Vol. 51, No. 5 ( 2014-09), p. 602-605
Abstract:
We previously reported that glycated albumin (GA) levels increased in an age-dependent manner in infancy. In order to determine whether this phenomenon is true from infancy to adulthood, we investigated the GA levels in non-diabetic subjects of a wide range of age. Methods GA levels of 376 non-diabetic subjects [average age, 31.8 ± 23.8 years (4 days–78 years)] were determined. A relationship between GA and logarithmically transformed age [log(age)] was analysed. Results GA levels were significantly positively correlated with log(age) [ R = 0.865, P 〈 0.0001, GA = 1.77 × log(day) + 6.55]. Based on a regression line, we established the formula for adjusting GA levels according to age. Conclusion We showed that GA increases with age from infancy to adulthood and that normal GA levels are demonstrated as a simple regression formula with log(age). This formula allowing us to use the adult reference range has the potential for treatment monitoring of diabetic patients regardless of age.
Type of Medium:
Online Resource
ISSN:
0004-5632
,
1758-1001
DOI:
10.1177/0004563213512617
Language:
English
Publisher:
SAGE Publications
Publication Date:
2014
detail.hit.zdb_id:
2041298-8
