In:
Clinical Pediatrics, SAGE Publications, Vol. 36, No. 6 ( 1997-06), p. 321-326
Kurzfassung:
Among 145 patients treated with recombinant human growth hormone (GH), four devel oped sleep apnea (two obstructive, two mixed) associated with tonsillar and adenoidal hypertrophy in three. These four patients had no local risk factors predisposing to upper airway obstruction (i.e., frequent pharyngitis or sinusitis). Clinical and/or polysomnographic features of sleep apnea improved following cessation of GH therapy in one patient, and following tonsillectomy and adenoidectomy in all patients. The present observations indicate that, albeit rarely, obstructive and/or central sleep apnea may occur in children treated with GH. Polysomnography should be considered if symptoms of snoring, interrupted sleep, daytime somnolence—particularly if associated with tonsillar hypertrophy—appear in children during GH therapy.
Materialart:
Online-Ressource
ISSN:
0009-9228
,
1938-2707
DOI:
10.1177/000992289703600602
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
1997
ZDB Id:
2066146-0
