In:
Asian Cardiovascular and Thoracic Annals, SAGE Publications, Vol. 8, No. 4 ( 2000-12), p. 315-321
Kurzfassung:
The relationship between preoperative lipid status and postoperative thrombocytosis was evaluated in 130 patients who were grouped according to their preoperative serum cholesterol level: group A, cholesterol ≥ 6.2 mmol·L −1 (n = 40); group B, cholesterol 〈 6.2 but ≥ 5.2 mmol·L −1 (n = 22); group C, cholesterol 〈 5.2 but ≥ 4.7 (n = 18); and group D, cholesterol 〈 4.7 mmol·L −1 (n = 50). Patient demo-graphics, angiography findings, and operative data did not differ between the groups. The incidence of postoperative thrombocytosis (platelet count ≥ 400,000/μL) was 82.5%, 36.4%, 16.7%, and 2.0% for groups A to D, respectively. Patients who developed thrombocytosis had a significantly higher preoperative ratio of total cholesterol to high-density lipoprotein cholesterol than those with normal platelet counts. The incidence of thrombocytosis directly correlated with the preoperative total cholesterol level. A distinct separation point seems to be a total cholesterol level of 4.7 mmol·L −1 . Preoperative lipid control with statins is emphasized to avoid postoperative thrombocytosis and thrombotic complications. The total cholesterol/high-density lipoprotein cholesterol ratio seems to be the best indicator of the risk of developing postoperative thrombocytosis.
Materialart:
Online-Ressource
ISSN:
0218-4923
,
1816-5370
DOI:
10.1177/021849230000800405
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
2000
ZDB Id:
2044527-1
