In:
International Journal of Immunopathology and Pharmacology, SAGE Publications, Vol. 24, No. 1_suppl2 ( 2011-01), p. 1-6
Kurzfassung:
Bone tissue engineering typically uses biomaterial scaffolds, osteoblasts or cells that can become osteoblasts, and biophysical stimulations to promote cell attachment and differentiation. In this study, we investigated the effects of an electromagnetic wave on mesenchymal stromal cells isolated from the bone marrow and seeded upon gelatin cryogel disks. In comparison with control conditions without electromagnetic stimulus, the electromagnetic treatment (magnetic field, 2 mT; frequency, 75 Hz) increased the cell proliferation and differentiation and enhanced the biomaterial surface coating with bone extracellular matrix proteins. Using this tissue-engineering approach, the gelatin biomaterial, coated with differentiated cells and their extracellular matrix proteins, may be used in clinical applications as an implant for bone defect repair.
Materialart:
Online-Ressource
ISSN:
2058-7384
,
2058-7384
DOI:
10.1177/03946320110241S201
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
2011
ZDB Id:
2505963-4
