In:
Journal of Biological Rhythms, SAGE Publications, Vol. 14, No. 3 ( 1999-06), p. 185-189
Kurzfassung:
The authors examined levels of melatonin in the plasma and various tissues in intact, pinealectomized, and pineal stalk–deflected zebra finches kept under 12:12 LD to determine if the melatonin found in the gastrointestinal tract is secreted in a circadian manner. In intact and pineal stalk-deflected birds, there is a clear day-night rhythm in melatonin content of the plasma, pineal gland, eyes, proventriculus, crop, duodenum, jejunum/ileum, colon, heart, and liver. In contrast, pinealectomy abolished the day-night rhythm. These results indicate that most of the melatonin present in the gastrointestinal tract of zebra finches is of pineal origin. However, some melatonin remained. This suggests that this melatonin may be locally synthesized and has paracrine and/or autocrine functions. Nonetheless, the results do not lend support to the contention that this putative melatonin secretion by the gastrointestinal tract is circadian.
Materialart:
Online-Ressource
ISSN:
0748-7304
,
1552-4531
DOI:
10.1177/074873099129000588
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
1999
ZDB Id:
2018064-0
SSG:
12
