In:
Multiple Sclerosis Journal, SAGE Publications, Vol. 20, No. 11 ( 2014-10), p. 1439-1442
Kurzfassung:
More than 80% of the human genome is biochemically active, whereas less than 3% of the genome encodes proteins. The emerging field of non-coding ribonucleic acids (RNAs) that are products of the genome, but do not program proteins, has revolutionized our understanding of cell biology. This was followed by a growing interest in the role of non-coding RNAs in the pathogenesis of human diseases, including multiple sclerosis (MS). In April 2013, a symposium in Warsaw, Poland, was the first meeting entirely dedicated to advances in the understanding of the roles of various subclasses of non-coding RNAs and showcased their involvement in autoimmune demyelination and MS. New mechanisms of action of small non-coding RNAs, as well as the advent of long non-coding RNAs were discussed, including the potential role of non-coding RNAs as MS biomarkers and their use for therapeutic intervention in MS.
Materialart:
Online-Ressource
ISSN:
1352-4585
,
1477-0970
DOI:
10.1177/1352458514521518
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
2014
ZDB Id:
2008225-3
