In:
Natural Product Communications, SAGE Publications, Vol. 4, No. 1 ( 2009-01), p. 1934578X0900400-
Abstract:
Chemical modifications of parthenin, a naturally occurring bioactive sesquiterpenoid, were carried out in regio- and stereoselective manners using various inexpensive reagents to form different natural and unnatural analogues. Reactions including dehydration, reduction, alkylation, addition and hydroxylation have been studied. In some of the analogues, the α-methylene-γ-lactone moiety, which plays a vital role for bioactivity of parthenin, remained intact.
Type of Medium:
Online Resource
ISSN:
1934-578X
,
1555-9475
DOI:
10.1177/1934578X0900400104
Language:
English
Publisher:
SAGE Publications
Publication Date:
2009
detail.hit.zdb_id:
2430442-6
SSG:
15,3