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T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia

Mardiros, Armen ; Dos Santos, Cedric ; McDonald, Tinisha ; [et al.]

American Society of Hematology ; 2013

In: Blood Vol. 122, No. 18 ( 2013-10-31), p. 3138-3148

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In: Blood, American Society of Hematology, Vol. 122, No. 18 ( 2013-10-31), p. 3138-3148

Abstract: CD123 CAR T cells specifically target CD123+ AML cells. AML patient-derived T cells can be genetically modified to lyse autologous tumor cells.

Type of Medium: Online Resource

ISSN: 0006-4971 , 1528-0020

URL: Article

DOI: 10.1182/blood-2012-12-474056

RVK:

XA 33000

RVK:

XA 10000

Language: English

Publisher: American Society of Hematology

Publication Date: 2013

detail.hit.zdb_id: 1468538-3

detail.hit.zdb_id: 80069-7

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Kooperativer Bibliotheksverbund

Berlin Brandenburg