In:
Blood, American Society of Hematology, Vol. 126, No. 21 ( 2015-11-19), p. 2415-2423
Abstract:
Factor V and protein S are required for sepsis mortality reduction and suppression of inflammatory gene expression by activated protein C. The R506Q mutation (Leiden mutation) abrogates the anti-inflammatory cofactor function of factor V for activated protein C.
Type of Medium:
Online Resource
ISSN:
0006-4971
,
1528-0020
DOI:
10.1182/blood-2015-05-644401
Language:
English
Publisher:
American Society of Hematology
Publication Date:
2015
detail.hit.zdb_id:
1468538-3
detail.hit.zdb_id:
80069-7