In:
Blood, American Society of Hematology, Vol. 130, No. 26 ( 2017-12-28), p. 2860-2871
Abstract:
TKI-resistant CML patients display persistent BMP pathway alterations in leukemic immature cells and their niche. A subpopulation of TKI-resistant leukemic stem cells survives through binding of BMP4 to BMPR1b, which preserves TWIST-1-expressing cells.
Type of Medium:
Online Resource
ISSN:
0006-4971
,
1528-0020
DOI:
10.1182/blood-2017-08-801019
Language:
English
Publisher:
American Society of Hematology
Publication Date:
2017
detail.hit.zdb_id:
1468538-3
detail.hit.zdb_id:
80069-7