In:
European Respiratory Journal, European Respiratory Society (ERS), Vol. 49, No. 4 ( 2017-04), p. 1601486-
Abstract:
Sleep disordered breathing (SDB) is common in patients with coronary disease, but its impact on post-operative recovery after coronary artery bypass graft surgery (CABG) is unclear. We therefore determined the effects of SDB on post-operative outcome after elective CABG. In this prospective two-centre study, 219 patients due to receive elective CABG underwent cardiorespiratory polygraphy for SDB prior to surgery and were monitored for post-operative complications. The primary end-point was a composite of 30-day mortality or major post-operative complications (cardiac, respiratory, surgical, infectious, acute renal failure or stroke). Key secondary end-points were single components of the primary end-point. SDB was present in 69% and moderate/severe SDB in 43% of the CABG patients. There was no difference in the composite of 30-day mortality or major postoperative complications between patients with and without SDB (OR 0.97, 95% CI 0.49–1.96) and between patients with moderate/severe SDB and no/mild SDB (OR 1.07, 95% CI 0.55–2.06). However, moderate/severe SDB was associated with higher rates of mortality (crude OR 10.1, 95% CI 1.22–83.5), sepsis (OR 2.96, 95% CI 1.17–7.50) and respiratory complications (OR 2.85, 95% CI 1.46–5.55). Although SDB was not associated with higher overall morbidity/mortality, moderate/severe SDB may increase the risk of death, and septic and respiratory complications, after elective CABG.
Type of Medium:
Online Resource
ISSN:
0903-1936
,
1399-3003
DOI:
10.1183/13993003.01486-2016
DOI:
10.1183/13993003.01486-2016.Supp1
DOI:
10.1183/13993003.01486-2016.Supp2
Language:
English
Publisher:
European Respiratory Society (ERS)
Publication Date:
2017
detail.hit.zdb_id:
639359-7
detail.hit.zdb_id:
1499101-9