In:
BMC Infectious Diseases, Springer Science and Business Media LLC, Vol. 5, No. 1 ( 2005-12)
Abstract:
Fluoroquinolones or third generation cephalosporins are the drugs of choice for the treatment of typhoid fever. Treatment failure with fluoroquinolones has been reported in Asia and Europe. We report a case of ciprofloxacin treatment failure in typhoid fever in Cameroon. Case presentation A 29-year-old female patient with suspected typhoid fever from Kumba, Cameroon, yielded growth of Salmonella enterica serovar Typhi in blood culture. The isolate was resistant to nalidixic acid but sensitive to ciprofloxacin by disc diffusion test. However, the patient did not respond to treatment with ciprofloxacin, although the isolate was apparently susceptible to ciprofloxacin. Conclusion Treatment failure with ciprofloxacin in our case indicates the presence of nalidixic acid resistant S. enterica serovar Typhi (NARST) with reduced susceptibility to ciprofloxacin in Cameroon (Central Africa).
Type of Medium:
Online Resource
ISSN:
1471-2334
DOI:
10.1186/1471-2334-5-49
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2005
detail.hit.zdb_id:
2041550-3
