In:
World Journal of Surgical Oncology, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2023-08-23)
Abstract:
This study aimed to determine short-term and long-term outcomes according to time intervals after stenting and compared them with those of emergency surgery (ES) in colorectal cancer (CRC) with malignant obstruction. Methods CRC with malignant obstructions was reviewed retrospectively between January 2008 and July 2018. Of a total of 539 patients who visited the emergency room and underwent ES, 133 were enrolled in the ES group. Of a total of 567 patients who initially received stenting and subsequently underwent elective surgery, 220 were enrolled in the SEMS group. The interval between SEMS placement and elective surgery was classified as 〈 11 days, 11–17 days, and 〉 17 days. Results For those who received SEMS ( n = 220), those with a time interval of 11–17 days ( n = 97) had fewer hospital days than those with a time interval of 〈 11 days ( n = 68) (8 days vs. 15 days) and less stoma formation than those with a time interval of 〉 17 days ( n = 55) (1.0% vs. 14.6%). Multivariable analysis revealed a decreased risk of death for the group with a time interval of 11–17 days (20.6%) compared to the ES group (31.6%) (hazard ratio: 0.48; 95% confidence interval: 0.24–0.97). Disease-free survival was comparable between the SEMS and ES groups regardless of the time interval (log-rank p = 0.52). Conclusions The time interval of 11–17 days after stenting to elective surgery appeared to be associated with the most favorable outcomes.
Type of Medium:
Online Resource
ISSN:
1477-7819
DOI:
10.1186/s12957-023-03130-6
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2023
detail.hit.zdb_id:
2118383-1
