In:
International Journal of Retina and Vitreous, Springer Science and Business Media LLC, Vol. 6, No. 1 ( 2020-12)
Abstract:
To report novel findings and limitations from optical coherence tomography angiography (OCTA) in the evaluation of autoimmune retinopathy (AIR). Study design We retrospectively reviewed features of five patients diagnosed with AIR and five controls. OCTA scans were obtained and manually segmented to provide accurate measurements of foveal avascular zone (FAZ), vessel density, and retinal thickness at different levels. Results The total retina and superficial vessel density throughout the whole scan were similar between AIR and controls ( p = 0.14 and p = 0.11), whereas deep vessel density was decreased in AIR compared controls ( p = 0.02). Decreased vessel density was most pronounced in the parafoveal and perifoveal areas ( p = 0.01 and p = 0.01). AIR patients also had reduction of total retinal thickness in the perifoveal zone (p = 0.03), corresponding to outer retinal thinning ( p = 0.001). Conclusion This small series shows that AIR patients have reduced deep vessel density, particularly in the parafoveal and perifoveal regions and a decrease in macular thickness. These findings show correlation with the classic “flying saucer” sign seen on OCT.
Type of Medium:
Online Resource
ISSN:
2056-9920
DOI:
10.1186/s40942-020-00267-4
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2020
detail.hit.zdb_id:
2836254-8
