In:
Neurology, Ovid Technologies (Wolters Kluwer Health), Vol. 101, No. 13 ( 2023-09-26), p. e1364-e1369
Abstract:
The etiology of central retinal artery occlusion (CRAO) is unclear in approximately 50% of patients, suggesting pathomechanical heterogeneity; moreover, little is known about outcomes according to etiology. This study investigated whether the presence of an embolic source affects outcome in CRAO. Methods CRAO patients within 7 days of symptom onset were retrospectively enrolled. Clinical parameters, including initial and 1-month visual acuity, CRAO subtype, and brain images, were reviewed. CRAO etiology was categorized as CRAO with or without an embolic source (CRAO-E + and CRAO-E − ). Visual improvement was defined as a decrease in logarithm of the minimum angle of resolution ≥0.3 at 1 month. Results A total of 114 patients with CRAO were included. Visual improvement was noted in 40.4% of patients. Embolic sources were identified in 55.3% of patients, and visual improvement group rather than no improvement group was more commonly associated with the presence of an embolic source. In multivariable logistic regression analysis, CRAO-E + independently predicted visual improvement (odds ratio 3.00, 95% CI 1.15–7.81, p = 0.025). Discussion CRAO-E + was found to be associated with a better outcome. CRAO-E + may be more prone to recanalization than that CRAO-E − .
Type of Medium:
Online Resource
ISSN:
0028-3878
,
1526-632X
DOI:
10.1212/WNL.0000000000207445
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2023