In:
Exercise and Sport Sciences Reviews, Ovid Technologies (Wolters Kluwer Health), Vol. 49, No. 4 ( 2021-10), p. 253-259
Kurzfassung:
The age-related decline in muscle function is aggravated by a high-fat diet (HFD)-induced increase in fat mass. The hypothesis is that an HFD leads to a faster accumulation of intramyocellular lipids (IMCL) and an earlier onset of muscle dysfunction in old than in young-adult individuals. The IMCL accumulation is attenuated in young-adult organisms by an elevated oxidative capacity. Methionine restriction enhances mitochondrial biogenesis and is promising to combat obesity across the ages.
Materialart:
Online-Ressource
ISSN:
1538-3008
,
0091-6331
DOI:
10.1249/JES.0000000000000261
Sprache:
Englisch
Verlag:
Ovid Technologies (Wolters Kluwer Health)
Publikationsdatum:
2021
ZDB Id:
2083448-2
SSG:
31
