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    In: Journal of Yeungnam Medical Science, Yeungnam University College of Medicine, Vol. 40, No. 2 ( 2023-04-30), p. 187-192
    Abstract: Background: This study aimed to present the short- and midterm outcomes after complete atrioventricular canal defect (CAVC) repair using a single-patch technique.Methods: This study included 30 children who underwent surgical correction of the CAVC using a single-patch technique.Results: The median age of the patients was 5.7 months (interquartile range [IQR], 5.0–7.5 months), and 23 patients (76.7%) had type A CAVC. Fourteen patients (46.7%) were female and 17 (56.7%) had been diagnosed with Down syndrome. The in-hospital mortality rate was 0%. No deaths were observed during a median follow-up of 4 years (IQR, 3.5–5.0 years). Patients without Down syndrome were associated with late moderate mitral regurgitation (MR) (p=0.02). Late MR less than moderate degree was observed in 96.6%, 78.5%, and 50% of patients after 2, 4, and 5 years of follow-up, respectively, while late tricuspid valve regurgitation less than moderate degree was observed in 96.7%, 85.9%, and 59.0% of patients after 2, 4, and 6 years of follow-up, respectively. After a median follow-up of 4 years, only one patient had required surgical repair of a left ventricular outflow tract obstruction, which occurred 26 months after the first operation. Multivariable lo gistic regression analysis adjusted for the type of CAVC, sex, Down syndrome, age, and weight revealed that the absence of Down syndrome was a risk factor for late moderate MR (MR-2) (odds ratio, 0.05; 95% confidence interval, 0.006–0.50; p=0.01).Conclusion: A single-patch technique for CAVC surgical repair is a safe method with acceptable short- and midterm results.
    Type of Medium: Online Resource
    ISSN: 2799-8010
    Language: English
    Publisher: Yeungnam University College of Medicine
    Publication Date: 2023
    detail.hit.zdb_id: 3116917-X
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