In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 8 ( 2021-8-5), p. e0254427-
Kurzfassung:
Acute myocardial infarction with ST-segment elevation (STEMI) and obstructive coronary arteries (MI-CAD) are treated with primary percutaneous coronary interventions (pPCI), while patients with STEMI and non-obstructive coronary arteries (MINOCA), usually require non-invasive therapy. The aim of the study is to design a score for predicting suspected MINOCA among an overall group of STEMI patients. Materials and methods Based on the Polish national registry of PCIs, we evaluated patients between 2014 and 2019, and selected 526,490 subjects treated with PCI and 650,728 treated using only coronary angiography. These subjects were chosen out of 1,177,218 patients who underwent coronary angiography. Then, we selected 124,663 individuals treated with pPCI due to STEMI and 5,695 patients with STEMI and MINOCA. The score for suspected MINOCA was created using the regression model, while the coefficients calculated for the final model were used to construct a predictive model in the form of a nomogram. Results Patients with MINOCA differ significantly from those in the MI-CAD group; they were significantly younger, less often males and demonstrated smaller burden of concomitant diseases. The model allowed to show that patients who scored more than 600 points had a 19% probability of MINOCA, while for those scoring more than 650 points, the likelihood was 71%. The other end of the MINOCA probability scale was marginal for patients who scored less than 500 points ( 〈 .2%). Conclusions Based on the created MINOCA score presented in the current publication, we are able to distinguish MINOCA from MI-CAD patients in the STEMI group.
Materialart:
Online-Ressource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0254427
DOI:
10.1371/journal.pone.0254427.g001
DOI:
10.1371/journal.pone.0254427.g002
DOI:
10.1371/journal.pone.0254427.g003
DOI:
10.1371/journal.pone.0254427.t001
DOI:
10.1371/journal.pone.0254427.t002
DOI:
10.1371/journal.pone.0254427.t003
DOI:
10.1371/journal.pone.0254427.t004
DOI:
10.1371/journal.pone.0254427.t005
DOI:
10.1371/journal.pone.0254427.s001
DOI:
10.1371/journal.pone.0254427.s002
DOI:
10.1371/journal.pone.0254427.s003
DOI:
10.1371/journal.pone.0254427.r001
DOI:
10.1371/journal.pone.0254427.r002
DOI:
10.1371/journal.pone.0254427.r003
DOI:
10.1371/journal.pone.0254427.r004
DOI:
10.1371/journal.pone.0254427.r005
DOI:
10.1371/journal.pone.0254427.r006
DOI:
10.1371/journal.pone.0254427.r007
DOI:
10.1371/journal.pone.0254427.r008
Sprache:
Englisch
Verlag:
Public Library of Science (PLoS)
Publikationsdatum:
2021
ZDB Id:
2267670-3
